PI3K/Akt/mTOR

Sustains ESC self-renewal and pluripotency

Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases

Cyclooxygenase inhibitor

Dyrk1A/B inhibitor. Impairs NSCs self-renewal.

Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.

Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.