Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Necrostatin-5 (HB3994)
Description:Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.
Purity:>98%
Necrostatin-7 (HB3995)
Description:Necroptosis inhibitor. Shows no action at RIP1 kinase.
Purity:>98%
Neuropathiazol (HB3105)
Description:Selective neuronal differentiation inducer in hippocampal neural progenitors
Purity:>98%
22-NHC (inactive isomer) (HB3719)
Description:Inactive control compound for hedgehog signaling inhibitor 22-NHC
Purity:>98%
Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%