Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
Agistatin D (HB3745)
Description:Cholesterol biosynthesis inhibitor. Analog of agistatin A.
Purity:>98%
AICAR (HB2152)
Description:AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.
Purity:>99%
- Description:
Immunostimulant. Natural killer T cell stimulator.
Purity:>96%
Alprenolol hydrochloride (HB1734)
Description:Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.
Purity:>99%
Alsterpaullone (HB3754)
Description:Potent CDK1 inhibitor. Also shows activity at GSK-3β
Purity:>98%
Altenusin (HB3755)
Description:Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor.
Purity:>97%