Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
Necrostatin-5 (HB3994)
Description:Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.
Purity:>98%
Necrostatin-7 (HB3995)
Description:Necroptosis inhibitor. Shows no action at RIP1 kinase.
Purity:>98%
Neuropathiazol (HB3105)
Description:Selective neuronal differentiation inducer in hippocampal neural progenitors
Purity:>98%
22-NHC (inactive isomer) (HB3719)
Description:Inactive control compound for hedgehog signaling inhibitor 22-NHC
Purity:>98%
Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%