Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Agistatin D (HB3745)
Description:Cholesterol biosynthesis inhibitor. Analog of agistatin A.
Purity:>98%
AICAR (HB2152)
Description:AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.
Purity:>99%
- Description:
Immunostimulant. Natural killer T cell stimulator.
Purity:>96%
Alprenolol hydrochloride (HB1734)
Description:Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.
Purity:>99%
Alsterpaullone (HB3754)
Description:Potent CDK1 inhibitor. Also shows activity at GSK-3β
Purity:>98%
Altenusin (HB3755)
Description:Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor.
Purity:>97%