DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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7-Amino-4-methylcoumarin (HB0694)
Description:Highly sensitive and selective fluorogenic H2S probe.
Purity:>98%
- Description:
Ribosome-borne protein folding activity (RPFA) inhibitor
Purity:>99%
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6-Aminophenanthridine (HB3730)
Description:Ribosome-borne protein folding activity (RPFA) inhibitor
Purity:>97%
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4-Aminopyridine (4-AP) (HB1073)
Description:Non-selective voltage gated K+ channel blocker
Purity:>99%
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Amisulpride (HB1879)
Description:Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.
Purity:>98%
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Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
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