Cytokine Storm / Immune response signaling

Filters

Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

Items 11-13 of 13

Set Descending Direction
  1. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $87
    Qty:
    Pack:
    10mg
    Price:
    $131
    Qty:
    Pack:
    25mg
    Price:
    $325
    Qty:
    Pack:
    50mg
    Price:
    $547
    Qty:
  2. SB 431542 (HB3555)

    4  Reviews
    Top Reviews:
    100% of 100
    Add Your Review
    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    5mg
    Price:
    $153
    Free trial
    Qty:
    Pack:
    2x5mg
    Price:
    $240
    Qty:
    Pack:
    10mg
    Price:
    $233
    Qty:
    Pack:
    25mg
    Price:
    $508
    Qty:
    Pack:
    50mg
    Price:
    $959
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $154
    Qty:
  3. 6  Reviews
    Top Reviews:
    100% of 100
    Add Your Review
    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $119
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    5x10mg
    Price:
    $754
    Qty:
    Pack:
    25mg
    Price:
    $325
    Qty:
    Pack:
    50mg
    Price:
    $564
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
    Qty:
Page