Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 151-160 of 162

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  1. Pack:
    1g
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    $73
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    Pack:
    50mM (add 1ml water)
    Price:
    $41
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  2. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
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    Pack:
    10mg
    Price:
    $110
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    Pack:
    25mg
    Price:
    $246
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    Pack:
    50mg
    Price:
    $446
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  3. Pack:
    10mg
    Price:
    $135
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    Pack:
    50mg
    Price:
    $565
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  4. 6  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
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    Pack:
    2mg
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    Pack:
    5mg
    Price:
    $119
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    Pack:
    10mg
    Price:
    $168
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    Pack:
    5x10mg
    Price:
    $754
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    Pack:
    25mg
    Price:
    $325
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    Pack:
    50mg
    Price:
    $564
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    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
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  5. YM-254890 (HB6283)

    Description:

    Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $421
    Qty:
  6. ZD 7288 (HB1152)

    4  Reviews
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    Description:

    HCN channel blocker. Modulates sino-atrial node function.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    50mg
    Price:
    $556
    Qty:
  7. Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    50mg
    Price:
    $540
    Qty:
  8. Pack:
    10mg
    Price:
    $78
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    Pack:
    25mg
    Price:
    $191
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    Pack:
    100mg
    Price:
    $547
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  9. Pack:
    500mL
    Price:
    $116
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    Pack:
    2x500mL
    Price:
    $185
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  10. Pack:
    500mL
    Price:
    $271
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    Pack:
    2x500mL
    Price:
    $406
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