DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligands. Researchers can make big savings on Hello Bio's DREADD ligands such as DCZ, CNO and C21, our prices are around 25-50% less than other suppliers.
Further information:Â DREADDs mini-review | Stability of Water-Soluble DREADD Ligands in Solution | CNO (freebase) - stability, solubility and use in the lab
- Description:
Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.
Purity:>98%
- Description:
Dihydrochloride salt of CNO - the prototypical DREADD activator
Purity:>98%
-
Deschloroclozapine (DCZ) (HB8555)
Description:Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.
Purity:>98%
- Description:
Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.
Purity:>98%
-
Iperoxo (HB9785)
Description:Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniGq DREADD receptor.
- Description:
Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.
Purity:>98%
-
±-Octopamine hydrochloride (HB2791)
Description:Invertebrate neurotransmitter. Chemogenetic DmOctβ1 receptor activator.
Purity:>99%
-
-
Diphenhydramine hydrochloride (DPH) (HB2617)
Description:Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.
Purity:>99%
