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Cytokines, chemokines & NF-κB/I-κB
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Cytokines and chemokines play an important role in the modulation of inflammation and acts as key modulators of inflammation by acting through a variety of complex pathways and interactions.
Proinflammatory cytokines activate the IKK complex and closely interact with NF-κB and JAK/STAT signaling.
Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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LIH383 (HB9242)
Description:Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
