Stem cells
Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These small molecules can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on high purity stem cell research tools such as ROCK inhibitor Y 27632, A83-01 and CHIR 99021 from Hello Bio - they are around half the price of other suppliers.
View products:  Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
Ouabain (HB1140)
Description:Selective Na+ / K+ ATPase inhibitor. Shows antiviral activity.
Purity:>98%
PD 0325901 (HB2240)
Description:Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.
Purity:>98%
Pifithrin-μ (HB3025)
Description:p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.
Purity:>99%
Remdesivir (HB9521)
Description:Adenosine triphosphate analog with broad-spectrum antiviral activity
Purity:>98%
RepSox (HB3301)
Description:Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.
Purity:>99%
RG 108 (HB1377)
Description:Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.
Purity:>99%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
Thiazovivin (HB3240)
Description:Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.
Purity:>97%
Tranylcypromine hydrochloride (HB1412)
Description:LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.
Purity:>98%