DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 301-310 of 313

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  1. 6  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $119
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    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    5x10mg
    Price:
    $754
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    Pack:
    25mg
    Price:
    $325
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    Pack:
    50mg
    Price:
    $564
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    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
    Qty:
  2. YM-254890 (HB6283)

    Description:

    Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $421
    Qty:
  3. Z-DEVD-FMK (HB1282)

    Description:

    Irreversible, selective caspase 3 inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $299
    Qty:
    Pack:
    5mg
    Price:
    $1,211
    Qty:
  4. Z-DQMD-FMK (HB1283)

    Description:

    Cell permeable caspase 3 specific inhibitor

    Pack:
    1mg
    Price:
    $293
    Qty:
    Pack:
    5mg
    Price:
    $1,189
    Qty:
  5. Zebularine (HB1378)

    Description:

    DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $42
    Qty:
    Pack:
    5mg
    Price:
    $89
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  6. Pack:
    1mg
    Price:
    $186
    Qty:
  7. Description:

    Highly potent, selective, cell permeable proteasome inhibitor. More potent than MG-132.

    Purity:

    >95%

    Pack:
    200μg
    Price:
    $270
    Qty:
    Pack:
    1mg
    Price:
    $1,342
    Qty:
  8. Pack:
    10mg
    Price:
    $244
    Qty:
    Pack:
    50mg
    Price:
    $989
    Qty:
  9. Pack:
    10mg
    Price:
    $210
    Qty:
    Pack:
    50mg
    Price:
    $844
    Qty:
  10. Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $678
    Qty:
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