GluN2

TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

Potent, competitive NMDA receptor antagonist

AMPA receptor antagonist

Potent GluN2C / GluN2D subunit selective NMDA receptor antagonist

Selective ERα estrogen receptor agonist

Potent neural factor

Growth factor implicated in various nervous system functions.

Pro-form of the nerve growth factor (NGF) neurotrophin

Neurotrophic factor with neuroprotective effects

Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs