Recombinant human ProNGF protein

(HB9354)
Technical documents: Datasheet

Product overview

Name Recombinant human ProNGF protein
Biological description

Pro-form of the neurotrophin nerve growth factor (NGF) that is cleaved to release its C-terminal mature form.

proNGF binds to TrkA/p75NTR to mediate cell survival and to sortilin/p75NTR to promote apoptosis.

Alternative names Recombinant Human Pro-Nerve Growth Factor, Human Pro-NGF, ProNGF, NGFB.
Purity >95%
Description Pro-form of the nerve growth factor (NGF) neurotrophin
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Solubility & Handling

Storage instructions -20°C
Solubility overview To make a stock solution, reconstitute in 1xPBS to a concentration no less than 100 μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 25
Source E. Coli.
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB and 0.25M NaCl (pH 7.2)

References for Recombinant human ProNGF protein

References are publications that support the biological activity of the product

3 Item(s)