Recombinant human ProNGF protein

(HB9354)
Technical documents: Datasheet

Product overview

Name Recombinant human ProNGF protein
Biological description

Pro-form of the neurotrophin nerve growth factor (NGF) that is cleaved to release its C-terminal mature form.

proNGF binds to TrkA/p75NTR to mediate cell survival and to sortilin/p75NTR to promote apoptosis.

Alternative names Recombinant Human Pro-Nerve Growth Factor, Human Pro-NGF, ProNGF, NGFB.
Purity >95%
Description Pro-form of the nerve growth factor (NGF) neurotrophin
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Solubility & Handling

Storage instructions -20°C
Solubility overview To make a stock solution, reconstitute in 1xPBS to a concentration no less than 100 μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
UniProt ID P01138
Molecular Weight 25
Source E. Coli.
Structure image  Chemical Structure
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB and 0.25M NaCl (pH 7.2)

References for Recombinant human ProNGF protein

References are publications that support the biological activity of the product

3 Item(s)