Ligand-gated ion channel

Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3Kainate | NMDA | P2X | Neuroscience Research Tools

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    Description:

    Non-competitive AMPA receptor antagonist. Also blocks kainate GluK3 homomeric receptors.

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    >98%

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  4. Hypotaurine (HB2656)

    Description:

    Non-selective endogenous glycine receptor agonist 

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    >95%

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  7. IEM-1460 (HB0338)

    Description:

    Competitive, selective, GluA2 (GluR2)-lacking AMPA receptor blocker

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    >98%

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  8. Ifenprodil (HB0339)

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    Description:

    Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor

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    >99%

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