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Biological Data

Biological description Inhibitory neurotransmitter. Also acts as NMDA receptor co-agonist. Prevents Ca2+-independent receptor desensitization.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name Aminoethanoic acid
Molecular Weight 75.07
Chemical structure Glycine  [56-40-6] Chemical Structure
Molecular Formula C2H5NO2
CAS Number 56-40-6
PubChem identifier 750
SMILES C(C(=O)O)N
InChi InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChiKey DHMQDGOQFOQNFH-UHFFFAOYSA-N
MDL number MFCD00008131
Appearance White solid

References for Glycine

References are publications that support the biological activity of the product
  • Glycine/NMDA receptor antagonists as potential CNS therapeutic agents: ACEA-1021 and related compounds.

    Cai SX (2006) Curr Top Med Chem 6(7) : 651-62.
  • Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.

    Danysz W et al (1998) Pharmacol Rev 50(4) : 597-664.
  • Glycine receptors: heterogeneous and widespread in the mammalian brain.

    Betz H (1991) Trends Neurosci 14(10) : 458-61.
Publications
These publications cite the use of Glycine purchased from Hello Bio:
  • Subunit-Specific Photocontrol of Glycine Receptors by Azobenzene-Nitrazepam Photoswitcher

    Maleeva G et al (2021) eNeuro 8(1)
    PubMedID: 33298457

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