Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 31-40 of 139

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    10mg
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    $127
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    50mg
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    $572
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  2. 12  Reviews
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    Description:

    Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $54
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    Pack:
    10mg
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    $107
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    50mg
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    $441
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    Pack:
    10mM (add 1ml water)
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    $58
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    20mM (add 1ml water)
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    $136
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  3. Compound E (HB3849)

    Description:

    Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $373
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  4. Concanamycin B (HB3850)

    Description:

    Specific vacuolar-type H+-ATPase inhibitor

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $193
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    Pack:
    500μg
    Price:
    $575
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  5. Pack:
    100μg
    Price:
    $198
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    Pack:
    500μg
    Price:
    $689
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  6. Pack:
    10mg
    Price:
    $127
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    Pack:
    50mg
    Price:
    $493
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  7. Pack:
    5mg
    Price:
    $78
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    Pack:
    10mg
    Price:
    $144
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    50mg
    Price:
    $537
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    Pack:
    100mg
    Price:
    $791
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  8. Pack:
    1mg
    Price:
    $70
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    Pack:
    10mg
    Price:
    $328
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    Pack:
    50mg
    Price:
    $1,364
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    Pack:
    10mM (add 1ml water)
    Price:
    $103
    Qty:
  9. Pack:
    5mg
    Price:
    $78
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    Pack:
    25mg
    Price:
    $311
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    Pack:
    10mg
    Price:
    $74
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