Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 11-20 of 139

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  1. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >98%

    Pack:
    1g
    Price:
    $127
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  2. Pack:
    100mg
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    $56
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    Pack:
    1g
    Price:
    $436
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    Pack:
    100mM (add 1ml water)
    Price:
    $41
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  3. D-AP5 (HB0225)

    48  Reviews
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    Description:

    Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $45
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    Pack:
    10mg
    Price:
    $116
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    Pack:
    50mg
    Price:
    $495
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    Pack:
    100mg
    Price:
    $685
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    Pack:
    50mM (add 1ml water)
    Price:
    $161
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    Pack:
    100mM (add 1ml water)
    Price:
    $289
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  4. L-Ascorbic acid (HB1238)

    Description:

    Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
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    Pack:
    1g
    Price:
    $28
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    Pack:
    25g
    Price:
    $42
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    Pack:
    100g
    Price:
    $100
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  5. Bafilomycin A1 (HB1125)

    2  Reviews
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    Description:

    Highly potent, selective V-ATPase inhibitor. Autophagy inhibitor.

    Purity:

    >98%

    Pack:
    10μg
    Price:
    $110
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    Pack:
    100μg
    Price:
    $303
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  6. Description:

    L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $124
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    Pack:
    50mg
    Price:
    $517
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  7. Description:

    Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

    Pack:
    2μg
    Price:
    $65
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    Pack:
    10μg
    Price:
    $260
    Qty:
  8. 4  Reviews
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    Description:

    Thymidine analog. Widely used to identify proliferating cells, enhances Yamanaka factor reprogramming

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $54
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    Pack:
    500mg
    Price:
    $78
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    Pack:
    1g
    Price:
    $133
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    Pack:
    5g
    Price:
    $409
    Qty:
  9. Description:

    Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $107
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    Pack:
    25mg
    Price:
    $464
    Qty:
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