Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 191-200 of 313

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  1. Description:

    Water soluble, potent protein phosphatase 1 and 2A inhibitor

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $230
    Qty:
  2. Description:

    LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $70
    Qty:
    Pack:
    5mg
    Price:
    $213
    Qty:
  3. Oligomycin A (HB4488)

    Description:

    Inhibitor of mitochondrial function

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $168
    Qty:
  4. Pack:
    50mg
    Price:
    $506
    Qty:
  5. Pack:
    100mg
    Price:
    $62
    Qty:
  6. Pack:
    10mg
    Price:
    $102
    Qty:
    Pack:
    50mg
    Price:
    $406
    Qty:
  7. Paxilline (HB1056)

    Description:

    Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $147
    Qty:
  8. Pack:
    50mg
    Price:
    $529
    Qty:
  9. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $28
    Qty:
    Pack:
    5×2mg
    Price:
    $115
    Qty:
    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $308
    Qty:
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