Neuroscience Marker Antibodies

A human brain contains around 86 billion neurones and 85 billion non-neural cells. Within this vast array of cells is a remarkable degree of heterogeneity and specialisation which are determined by the differential expression of thousands of gene products. This differential protein expression between cell types is used to identify specific cell types using marker antibodies. At Hello Bio we provide a range of markers to identify different cell types found in the central nervous system.

Neuronal Markers Secondary antibodies are conjugated to fluorophores, enzymes or proteins to enable visualisation and quantification of target proteins labeled with primary antibodies.   General Neuronal | Dopaminergic | GABAergic | Activity	Glial Markers Tags are proteins or peptides that are fused to a protein of choice in order to enable easy visualisation, tracking or purification.   Astrocytes | Microglia	Oligodendrocyte and Schwann Cell Markers Loading controls are antibodies that detect a highly expressed protein in a certain cell type and that are used to normalize gel loading differences and enable western blot quantification.

Neuronal Markers

Neurons are the central information processing unit in the nervous system and have remarkable heterogeneity dependent upon their location and function. Various neural markers are available that express in different cellular compartments and neuron subtypes. We have curated a collection of general use highly reliable antibodies that are excellent markers of neurons.

General Neuronal Markers

General neuronal markers are proteins expressed ubiquitously across all neuronal subtypes, regardless of function or mode of neurotransmission. They are useful for a wide range of experiments where protein expression needs localising to a neuron.

Anti-βIII Tubulin antibody ValidAb™	Anti-βIII Tubulin antibody ValidAb™	Anti-MAP2 antibody ValidAb™	Anti-MAP2 antibody ValidAb™	Anti-NeuN antibody ValidAb™
HB6639	HB8947	HB9587	HB6581	HB6429
Mouse Monoclonal	Chicken Polyclonal	Mouse Monoclonal	Chicken Polyclonal	Mouse Monoclonal
Anti-NeuN antibody ValidAb™	Anti-NeuN antibody ValidAb™	Anti-α-Synuclein antibody ValidAb™	Anti-Neurofilament L (NF-L) antibody ValidAb™	Anti-Neurofilament L (NF-L) antibody ValidAb™
HB6498	HB9493	HB6378	HB6433	HB7266
Rabbit Polyclonal	Goat Polyclonal	Mouse Monoclonal	Mouse Monoclonal	Rabbit Monoclonal
Anti-Neurofilament M (NF-M) antibody ValidAb™
HB7849
Mouse Monoclonal

GABAergic Markers

GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system, playing a crucial role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. Dysregulation of GABAergic signaling is implicated in various neurological disorders, including epilepsy, anxiety, and depression.

Anti-GAT1 antibody ValidAb™	Anti-VGAT antibody ValidAb™	Anti-Parvalbumin antibody ValidAb™	Anti-Calbindin antibody ValidAb™	Anti-Calretinin antibody ValidAb™
HB7632	HB6714	HB6457	HB6396	HB6494
Rabbit Polyclonal	Rabbit Polyclonal	Mouse Monoclonal	Mouse Monoclonal	Rabbit Polyclonal

Dopaminergic Markers

Anti-Tyrosine hydroxylase antibody ValidAb™	Anti-Tyrosine hydroxylase antibody ValidAb™	Anti-Tyrosine hydroxylase antibody ValidAb™
HB7167	HB6605	HB6589
Mouse Monoclonal	Rabbit Polyclonal	Chicken Polyclonal

Neuronal Activity Markers

Neuronal activity markers like c-Fos are essential tools in neuroscience research, as they serve as indicators of neuronal activation in response to various stimuli or experiences. When neurons become active, c-Fos is rapidly expressed, allowing researchers to map which populations of neurons are involved in specific behaviors or responses. This temporal and spatial profiling of neuronal activity helps to elucidate the underlying mechanisms of learning, memory, and other cognitive functions. 

Anti-c-Fos antibody ValidAb™	Anti-c-Fos antibody ValidAb™
HB8006	HB6593
Mouse Monoclonal	Rabbit Polyclonal

Glial Markers

Glial cells play essential roles in the central nervous system, providing support, protection, and insulation for neurons, as well as regulating the extracellular environment and facilitating neurotransmission. They are involved in various functions, including the maintenance of homeostasis, the response to injury, and the modulation of synaptic activity. 

Astrocyte Markers

Astrocytes are a sub-type of glial cell whose principal role is to support the healthy function of neurones in the nervous system. Astrocytes perform this role through carrying out a range of activities including but not limited to supplying glucose and lactate to neurones, providing structural support, uptake and release of various neurotransmitters and regulating local ion concentration.

Anti-GFAP antibody ValidAb™	Anti-GFAP antibody ValidAb™	Anti-GFAP antibody ValidAb™	Anti-GFAP antibody ValidAb™
HB8267	HB7592	HB6406	HB8001
Mouse Monoclonal	Goat Polyclonal	Chicken Polyclonal	Rabbit Polyclonal

Microglial Markers

Microglia are specialized immune cells in the central nervous system that play a crucial role in maintaining brain health by monitoring and responding to potential threats.

Anti-IBA1 antibody ValidAb™
HB7847
Rabbit Polyclonal

Oligodendrocyte and Schwann Cell Markers

Anti-Myelin Basic Protein (MBP) antibody ValidAb™
HB8014
Mouse Monoclonal

Related Content

Secondary Antibodies and Streptavidins Secondary antibodies are conjugated to fluorophores, enzymes or proteins to enable visualisation and quantification of target proteins labeled with primary antibodies.   AF488 | JF525 | JF549 | JF646 | HRP | Biotin | Streptavidin	Tag Antibodies Tags are proteins or peptides that are fused to a protein of choice in order to enable easy visualisation, tracking or purification.   GFP | mCherry | GST	Loading Controls Loading controls are antibodies that detect a highly expressed protein in a certain cell type and that are used to normalize gel loading differences and enable western blot quantification.   GAPDH | Beta Tubulin | HSP60 | Histone H3