Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 21-30 of 134

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    10mg
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    $173
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    50mg
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    $718
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  5. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
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    2mg
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    5×2mg
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    $180
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    Pack:
    10mg
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    $175
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    5mg
    Price:
    $112
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    25mg
    Price:
    $427
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    50mg
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    $727
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
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  6. Pack:
    10mg
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    $127
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    50mg
    Price:
    $572
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  7. 12  Reviews
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    Description:

    Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $54
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    Pack:
    10mg
    Price:
    $107
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    50mg
    Price:
    $441
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    Pack:
    10mM (add 1ml water)
    Price:
    $58
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    Pack:
    20mM (add 1ml water)
    Price:
    $136
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  8. Compound E (HB3849)

    Description:

    Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $373
    Qty:
  9. Concanamycin B (HB3850)

    Description:

    Specific vacuolar-type H+-ATPase inhibitor

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $193
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    Pack:
    500μg
    Price:
    $575
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  10. Pack:
    100μg
    Price:
    $198
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    Pack:
    500μg
    Price:
    $689
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