Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%
L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
Bafilomycin A1 (HB1125)
Description:Highly potent, selective V-ATPase inhibitor. Autophagy inhibitor.
Purity:>98%
Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
- Description:
Fluorescent β2 adrenoceptor antagonist
Caffeine (HB2846)
Description:Non-selective, competitive adenosine receptor antagonist / PDE inhibitor
Calphostin C (HB0160)
Description:Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex
Purity:>95%
Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%
(S)-4-Carboxyphenylglycine (HB0049)
Description:Competitive, selective group 1 mGlu antagonist
Purity:>99%