Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
A 769662 (HB1351)
Description:Potent, reversible AMPK activator. Inhibits MSC proliferation.
Purity:>98%
AICAR (HB2152)
Description:AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.
Purity:>99%
L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
Recombinant human BDNF protein (HB3485)
Description:Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.
8-Bromo-cAMP sodium salt (8-Br-cAMP) (HB0090)
Description:Cell permeable PKA activator
Purity:>99%
cAMPS-Sp triethylammonium salt (HB0566)
Description:Potent, specific cAMP-dependent protein kinases activator. Cell-permeable.
Purity:>98%
CAT335 (HB8146)
Description:K2P2.1 (TREK-1) modulator. Selectively and irreversibly activates TREK-1CG* but not wild-type K2P2.1 (TREK-1)
Purity:>98%