Potent, specific cAMP-dependent protein kinases activator. Cell-permeable. Unique tool for studying cAMP-dependent signaling due to it cell permeability and complete resistance to cyclic nucleotide phosphodiesterases. Shows higher resistance against cyclic nucleotide-dependent phosphodiesterases compared to dibutyryl-cAMP or 8-Br-cAMP. No metabolic side effects are shown.
Solubility & Handling
Solubility overview
Soluble in water (25mg/ml) or DMSO, DMF or methanol
Storage instructions
-20° (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase