Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
CGS 21680 hydrochloride (HB2097)
Description:Prototypic, selective A2A receptor agonist
Purity:>98%
(R,S)-CHPG sodium salt (HB0034)
Description:Selective mGluR5 agonist. Water soluble sodium salt.
Purity:>99%
Clozapine (HB1607)
Description:Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors
Purity:>99%
- Description:
Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.
Purity:>98%
CP 94253 dihydrochloride (HB1671)
Description:Potent, selective 5-HT1B receptor agonist
Purity:>98%