Stem cells
Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
View products: Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
(+)-Abscisic acid (HB4674)
Description:Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand
Purity:>99%
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(±)-Bay K 8644 (HB1209)
Description:L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.
Purity:>99%
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Dexamethasone (HB2521)
Description:Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.
Purity:>98%
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Dexamethasone (water-soluble) (HB6020)
Description:Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Â
Purity:>98%
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O-Phospho-L-serine (HB0475)
Description:Group III mGlu agonist. Increases stem cell neurogenesis.
Purity:>98%
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Pifithrin-α hydrobromide (HB2478)
Description:p53 inhibitor and Aryl hydrocarbon receptor agonist. Supresses ESC self renewal.
Purity:>98%
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Pioglitazone hydrochloride (HB2554)
Description:Selective PPARγ agonist. Enhances mESCs proliferation and survival.
Purity:>99%
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Purmorphamine (HB3412)
Description:Smo receptor agonist that activates the hedgehog pathway. Induces mesenchymal and iPSC differentiation.
Purity:>98%
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Rosiglitazone (HB2556)
Description:Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
Purity:>99%
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SAG (HB3107)
Description:Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.
Purity:>98%
