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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 131-140 of 236

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  1. LUF7982 (HB9905)

    Description:

    Novel Selective A2B covalent ligand. Binds irreversibly.

    Pack:
    50μg
    Price:
    $275
    Qty:
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  2. LY-367385 hydrochloride (HB5153)

    Description:

    Potent, highly selective mGlu1a antagonist. Water soluble.

    Pack:
    10mg
    Price:
    $132
    Qty:
    Pack:
    50mg
    Price:
    $502
    Qty:
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  3. LY 341495 (HB0394)

    Description:

    Potent, selective group II mGlu receptor antagonist

    Purity:

    >98%

    LY 341495
    Pack:
    1mg
    Price:
    $47
    Qty:
    Pack:
    10mg
    Price:
    $197
    Qty:
    Pack:
    50mg
    Price:
    $803
    Qty:
    Supporting Docs Add to Favorites

  4. LY 354740 hydrate (HB0397)

    Description:

    Potent, selective group II receptor agonist

    Purity:

    >95%

    LY 354740 hydrate
    Pack:
    1mg
    Price:
    $35
    Qty:
    Pack:
    5mg
    Price:
    $113
    Qty:
    Pack:
    10mg
    Price:
    $172
    Qty:
    Supporting Docs Add to Favorites

  5. 3-Methyladenine (HB2267)

    Description:

    PI-3K inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $118
    Qty:
    Pack:
    100mg
    Price:
    $169
    Qty:
    Supporting Docs Add to Favorites

  6. MCC950 sodium salt (HB4636)

    Description:

    Potent, selective NLRP3 inflammasome inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $90
    Qty:
    Pack:
    5mg
    Price:
    $359
    Qty:
    Pack:
    10mg
    Price:
    $580
    Qty:
    Supporting Docs Add to Favorites

  7. (RS)-MCPG (HB0037)

    Description:

    Non-selective group I and II mGluR antagonist

    Purity:

    >98%

    (RS)-MCPG
    Pack:
    10mg
    Price:
    $118
    Qty:
    Pack:
    50mg
    Price:
    $480
    Qty:
    Supporting Docs Add to Favorites

  8. MDCPG (HB1602)

    Description:

    Selective mGlu8 receptor antagonist

    MDCPG
    Pack:
    10mg
    Price:
    $263
    Qty:
    Pack:
    50mg
    Price:
    $1,112
    Qty:
    Supporting Docs Add to Favorites

  9. MDL 100907 (HB1780)

    Description:

    Potent and selective 5-HT2A receptor antagonist

    Purity:

    >98%

    MDL 100907
    Pack:
    10mg
    Price:
    $263
    Qty:
    Pack:
    50mg
    Price:
    $1,003
    Qty:
    Supporting Docs Add to Favorites

  10. Memantine hydrochloride (HB0407)

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    Description:

    Non-competitive NMDA receptor antagonist

    Purity:

    >98%

    Memantine inhibition of evoked NMDAR mediated EPSCs
    Pack:
    100mg
    Price:
    $183
    Qty:
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