Novel, selective A2B covalent ligand (apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action). Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors. LUF7982 covalently targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays. LUF7982 allows for novel ways to interrogate the A2BAR.
Sold under license from the Oncode Institute and Universiteit Leiden
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
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