DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 291-300 of 305

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  1. 6  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
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    Pack:
    2mg
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    Pack:
    5mg
    Price:
    $119
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    Pack:
    10mg
    Price:
    $168
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    Pack:
    5x10mg
    Price:
    $754
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    Pack:
    25mg
    Price:
    $325
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    Pack:
    50mg
    Price:
    $564
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    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
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  2. YM-254890 (HB6283)

    Description:

    Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $421
    Qty:
  3. Yoda 1 (HB5534)

    Description:

    Selective PIEZO1 channel activator

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $117
    Qty:
    Pack:
    50mg
    Price:
    $488
    Qty:
  4. ZD 7288 (HB1152)

    4  Reviews
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    Description:

    HCN channel blocker. Modulates sino-atrial node function.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    50mg
    Price:
    $556
    Qty:
  5. Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    50mg
    Price:
    $540
    Qty:
  6. Pack:
    10mg
    Price:
    $78
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    Pack:
    25mg
    Price:
    $191
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    Pack:
    100mg
    Price:
    $547
    Qty:
  7. Description:

    Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

    Purity:

    >99%

    Pack:
    500mg
    Price:
    $54
    Qty:
    Pack:
    1g
    Price:
    $75
    Qty:
  8. Pack:
    500mL
    Price:
    $116
    Qty:
    Pack:
    2x500mL
    Price:
    $185
    Qty:
  9. Pack:
    500mL
    Price:
    $271
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    Pack:
    2x500mL
    Price:
    $406
    Qty:
  10. Pack:
    100mL
    Price:
    $165
    Qty:
    Pack:
    250mL
    Price:
    $225
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    Pack:
    500mL
    Price:
    $413
    Qty:
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