Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 131-140 of 202

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  1. Description:

    Invertebrate neurotransmitter. Chemogenetic DmOctβ1 receptor activator.

    Purity:

    >99%

    Pack:
    1g
    Price:
    $31
    Qty:
    Pack:
    5g
    Price:
    $90
    Qty:
  2. Description:

    Water soluble, potent protein phosphatase 1 and 2A inhibitor

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $230
    Qty:
  3. Oligomycin A (HB4488)

    Description:

    Inhibitor of mitochondrial function

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $168
    Qty:
  4. Pack:
    10μg
    Price:
    $149
    Qty:
    Pack:
    100μg
    Price:
    $417
    Qty:
  5. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $147
    Qty:
  6. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $28
    Qty:
    Pack:
    5×2mg
    Price:
    $115
    Qty:
    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $308
    Qty:
  7. Pack:
    5mg
    Price:
    $91
    Qty:
    Pack:
    25mg
    Price:
    $367
    Qty:
  8. Pack:
    500μg
    Price:
    $163
    Qty:
    Pack:
    1mg
    Price:
    $261
    Qty:
  9. Pack:
    10mg
    Price:
    $234
    Qty:
    Pack:
    50mg
    Price:
    $934
    Qty:
  10. Pack:
    1g
    Price:
    $45
    Qty:
    Pack:
    5x1g
    Price:
    $193
    Qty:
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