Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 121-130 of 202

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  1. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

    Pack:
    5mg
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    10mg
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    $77
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    50mg
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    $325
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    Pack:
    10mM solution (in 1mL DMSO)
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    $125
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  2. Pack:
    10mg
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    $151
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    50mg
    Price:
    $641
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  3. MOG (35-55) (HB5273)

    Description:

    Myelin oligodendrocyte glycoprotein fragment. Induces experimental multiple sclerosis-like disease.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $176
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  4. Description:

    Selective P2Y1 antagonist. Inhibits platelet aggregation.

    Purity:

    >98%

    Pack:
    5mg
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    $113
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    Pack:
    10mg
    Price:
    $209
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    50mg
    Price:
    $911
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  5. MRS 2578 (HB1966)

    Description:

    Potent, selective P2Y6 receptor antagonist

    Purity:

    >95%

    Pack:
    10mg
    Price:
    $134
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  6. Pack:
    10mg
    Price:
    $128
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    Pack:
    50mg
    Price:
    $483
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    Pack:
    10mM (add 1ml water)
    Price:
    $50
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  7. Pack:
    250mg
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    Pack:
    1g
    Price:
    $33
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    Pack:
    5g
    Price:
    $107
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    10g
    Price:
    $188
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    25g
    Price:
    $432
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  8. 3  Reviews
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    Description:

    Selective GluA2- lacking, Ca2+ permeable AMPA / kainate receptor antagonist

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $71
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    Pack:
    10mg
    Price:
    $117
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    Pack:
    25mg
    Price:
    $230
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    Pack:
    50mg
    Price:
    $419
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  9. 29  Reviews
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    Description:

    Potent, selective, competitive AMPA receptor antagonist. Disodium salt.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $89
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    Pack:
    10mg
    Price:
    $185
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    Pack:
    50mg
    Price:
    $783
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    Pack:
    50mM (add 1ml water)
    Price:
    $441
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    Pack:
    100mM (add 1ml water)
    Price:
    $768
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  10. Pack:
    1mg
    Price:
    $34
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    Pack:
    5mg
    Price:
    $108
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    Pack:
    10mg
    Price:
    $165
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    Pack:
    25mg
    Price:
    $370
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