Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 291-300 of 313

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  1. VX 702 (HB1308)

    Description:

    Potent, selective ATP-competitive p38 MAPK inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $156
    Qty:
  2. VX 745 (HB1309)

    Description:

    Potent, selective p38α MAPK inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $211
    Qty:
    Pack:
    50mg
    Price:
    $814
    Qty:
  3. WHI-P 154 (HB1431)

    Description:

    Non-selective JAK3 inhibitor and potent EGFR inhibitor. Induces neural progenitor cell differentiation.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $83
    Qty:
    Pack:
    25mg
    Price:
    $298
    Qty:
  4. Pack:
    5mg
    Price:
    $90
    Qty:
    Pack:
    25mg
    Price:
    $350
    Qty:
  5. Pack:
    50mg
    Price:
    $833
    Qty:
  6. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $259
    Qty:
    Pack:
    50mg
    Price:
    $1,013
    Qty:
  7. Wortmannin (HB2778)

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    Description:

    Potent, selective, irreversible PI3-K inhibitor

    Purity:

    >99%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $246
    Qty:
    Pack:
    10mg
    Price:
    $455
    Qty:
  8. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $502
    Qty:
  9. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $110
    Qty:
    Pack:
    25mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $446
    Qty:
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