Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
Anti-GFP antibody ValidAbâ„¢ (HB6381)
Description:Monoclonal antibody (IgM) to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: MouseClonality: MonoclonalReactivity Tested: Species IndependentAnti-GFP antibody ValidAbâ„¢ (HB8365)
Description:Antibody to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: ChickenClonality: PolyclonalReactivity Tested: Species IndependentAnti-GST tag antibody ValidAbTM (HB9897)
Description:Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: MouseClonality: MonoclonalReactivity Tested: Species IndependentAnti-Histone H3 antibody ValidAbâ„¢ (HB6980)
Description:Antibody to Histone H3 - Histone protein used as a loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-HSP60 antibody ValidAbâ„¢ (HB7863)
Description:Antibody to HSP60 - loading control and mitochondrial marker for immunohistochemistry and immunocytochemistry. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat, HumanAnti-Ki-67 antibody ValidAbTM (HB7052)
Description:Antibody to Ki-67 - a widely used marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: HumanAnti-MAP2 antibody ValidAbTM (HB9587)
Description:Antibody to MAP2 - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, RatAnti-mCherry Antibody ValidAbâ„¢ (HB6512)
Description:Antibody to mCherry - red coloured fluorescent protein widely used as a tag in molecular biology
Host: RabbitClonality: PolyclonalReactivity Tested: Species Independent- Description:
Antibody to myelin basic protein (MBP) - marker for oligodendrocytes and Schwann cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Rat, Mouse (no staining) Anti-NeuN antibody ValidAbâ„¢ (HB6429)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat