PI3K/Akt/mTOR

Antimalarial. Apoptosis and autophagy inhibitor.

Potent JAK inhibitor

Na⁺ / K⁺ ATPase α subunit inhibitor. Antiviral.

Sphingosine 1-phosphate (S1P) receptor (S1P1, S1P3, S1P4, and S1P5) modulator

Dopamine receptor antagonist with partial D₂-like selectivity

Potent, selective mTOR inhibitor

Inhibits protein synthesis in gram-positive bacteria. Antibiotic.

mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

Potent, selective mTOR inhibitor

Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.