5-HT uptake & transport

Protein kinase inhibitor

Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.

Selective group I mGlu receptor agonist. Induces LTD.

Selective ERβ estrogen receptor agonist

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

Potent, selective μ-opioid receptor agonist

Potent, selective μ-opioid receptor agonist

Selective mineralcorticoid receptor antagonist

D₂ receptor antagonist

Selective serotonin reuptake inhibitor and σ1 receptor agonist