Product overview

Name Endomorphin-2
Purity >95%
Description Potent, selective μ-opioid receptor agonist
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Biological Data

Biological description Potent, selective μ-opioid receptor agonist (Ki values are 0.69 nM and 9.2 and 5.2 µM at μ, δ and κ receptors respectively). Endogenous peptide. Shows antinociceptive activity.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in water
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name Tyr-Pro-Phe-Phe-NH2
Molecular Weight 571.65
Molecular Formula C32H37N5O5
CAS Number 141801-26-5
PubChem identifier 5311081
SMILES C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N
InChiKey XIJHWXXXIMEHKW-LJWNLINESA-N

References for Endomorphin-2

References are publications that support the biological activity of the product
  • Opposite effects of neuropeptide FF on central antinociception induced by endomorphin-1 and endomorphin-2 in mice.

    Wang et al (2014) PLoS 9 : e103773
  • Endomorphin-1 and endomorphin-2: pharmacology of the selective endogenous mu-opioid receptor agonists.

    Horvath (2000) Pharmacol Ther 88 : 437-63
  • A potent and selective endogenous agonist for the mu-opiate receptor.

    Zadina et al (1997) Nature 386 : 499-502

3 Item(s)