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Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 19

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  1. Anti-βIII Tubulin antibody ValidAbTM (HB6639)

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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. β3-tubulin expression in the Purkinje cells of the cerebellum labelled by HB6639.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  2. Anti-β-tubulin antibody ValidAbTM (HB6491)

    Description:

    Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. ß-Tubulin and Neurofilament L expression in cultured rat neurones
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  3. Anti-c-Fos antibody ValidAbTM (HB8006)

    Description:

    Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse
    Figure 1. c-Fos expression in the dentate gyrus of TRAP2;Ai14 mice.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  4. Anti-GAPDH antibody ValidAbTM (HB9177)

    Description:

    Antibody to GAPDH - universal loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. GAPDH expression in various tissue lysates and preparations.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  5. Anti-GFAP antibody ValidAbTM (HB8267)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. GFAP expression in a rat cultured neurone preparation visualised using HB8267.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $316
    Qty:
    Supporting Docs Add to Favorites

  6. Anti-GFP antibody ValidAbTM (HB6381)

    Description:

    Monoclonal antibody (IgM) to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Figure 1. Specific HB6381 staining only in pEGFP-C2 transfected HEK293 cells.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  7. Anti-GST tag antibody ValidAbTM (HB9897)

    Description:

    Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Figure 1. Expression and purification of a GST-fusion protein monitored using HB9897.
    Pack:
    25μg
    Price:
    $141
    Qty:
    Pack:
    100μg
    Price:
    $315
    Qty:
    Supporting Docs Add to Favorites

  8. Anti-HSP60 antibody ValidAbTM (HB7863)

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    Description:

    Antibody to HSP60 - loading control and mitochondrial marker for immunohistochemistry and immunocytochemistry. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. HSP60 staining with HB7863 reveals the dense mitochondria in cultured rat neurones.
    Pack:
    25μg
    Price:
    $155
    Qty:
    Pack:
    100μg
    Price:
    $352
    Qty:
    Supporting Docs Add to Favorites

  9. Anti-Ki-67 antibody ValidAbTM (HB7052)

    Description:

    Antibody to Ki-67 - a widely used marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Human
    Figure 1. Ki-67 expression in proliferating HEK293T cells
    Pack:
    25μg
    Price:
    $139
    Qty:
    Pack:
    100μg
    Price:
    $310
    Qty:
    Supporting Docs Add to Favorites

  10. Anti-MAP2 antibody ValidAbTM (HB9587)

    Description:

    Antibody to MAP2 - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. MAP2 expression in cultured rat neurones visualised using HB9587.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites
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Applications
  1. ELISA
  2. ICC
  3. WB
  4. IHC(IF)
  5. Histoblot
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Target
  1. GluN1
  2. GFAP
  3. GAPDH
  4. NeuN
  5. Neurofilament L
  6. Beta III tubulin
  7. HSP60
  8. Neurofilament M
  9. GFP
  10. MAP2
  11. Tyrosine hydroxylase
  12. β-tubulin
  13. Myelin basic protein
  14. c-Fos
  15. Vimentin
  16. GST tag
  17. Parvalbumin
  18. Calbindin
  19. Ki-67