Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 30

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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  2. Description:

    Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $107
    Qty:
    Pack:
    25mg
    Price:
    $464
    Qty:
  3. Pack:
    100μg
    Price:
    $418
    Qty:
  4. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $180
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $427
    Qty:
    Pack:
    50mg
    Price:
    $727
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
    Qty:
  5. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $147
    Qty:
    Pack:
    10mg
    Price:
    $185
    Qty:
    Pack:
    50mg
    Price:
    $773
    Qty:
  6. Pack:
    100mg
    Price:
    $33
    Qty:
    Pack:
    1g
    Price:
    $90
    Qty:
  7. Pack:
    10mg
    Price:
    $81
    Qty:
    Pack:
    50mg
    Price:
    $382
    Qty:
  8. Pack:
    10mg
    Price:
    $88
    Qty:
  9. KU 0063794 (HB2250)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $259
    Qty:
    Pack:
    50mg
    Price:
    $1,047
    Qty:
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