DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 41-50 of 317

Set Descending Direction
  1. Description:

    Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $41
    Qty:
    Pack:
    50mg
    Price:
    $152
    Qty:
  2. Pack:
    1g
    Price:
    $33
    Qty:
    Pack:
    5g
    Price:
    $65
    Qty:
  3. CCG 1423 (HB3389)

    Description:

    Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $114
    Qty:
    Pack:
    50mg
    Price:
    $420
    Qty:
  4. Pack:
    10mg
    Price:
    $157
    Qty:
    Pack:
    50mg
    Price:
    $568
    Qty:
  5. Pack:
    5mg
    Price:
    $135
    Qty:
    Pack:
    25mg
    Price:
    $547
    Qty:
  6. Pack:
    1mg
    Price:
    $219
    Qty:
    Pack:
    5mg
    Price:
    $881
    Qty:
  7. Pack:
    5mg
    Price:
    $127
    Qty:
    Pack:
    25mg
    Price:
    $438
    Qty:
  8. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $180
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $427
    Qty:
    Pack:
    50mg
    Price:
    $727
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
    Qty:
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