DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 61-70 of 318

Set Descending Direction
  1. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $746
    Qty:
  2. Description:

    Potent SERCA1a inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $95
    Qty:
    Pack:
    50mg
    Price:
    $451
    Qty:
  3. Cyclosporin A (HB0220)

    Description:

    Potent calcineurin inhibitor. Inhibits MPTP opening.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $96
    Qty:
  4. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  5. Pack:
    100mg
    Price:
    $147
    Qty:
    Pack:
    500mg
    Price:
    $591
    Qty:
  6. Pack:
    5mg
    Price:
    $78
    Qty:
    Pack:
    25mg
    Price:
    $311
    Qty:
    Pack:
    10mg
    Price:
    $74
    Qty:
  7. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  8. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    25mg
    Price:
    $418
    Qty:
    Pack:
    50mg
    Price:
    $703
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
    Qty:
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