DREADD

Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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  1. Description:

    Phosphatase Inhibitor Cocktail solution (with Calyculin A) for the inhibition of serine/threonine and alkaline phosphatases.

    Pack:
    1mL
    Price:
    $83
    Qty:
    Pack:
    5x1mL
    Price:
    $282
    Qty:
  2. Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  3. Description:

    Potent dual PI3-K/mTOR inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    10mg
    Price:
    $211
    Qty:
    Pack:
    50mg
    Price:
    $823
    Qty:
  4. Pack:
    10mg
    Price:
    $110
    Qty:
    Pack:
    50mg
    Price:
    $442
    Qty:
  5. Pifithrin-μ (HB3025)

    Description:

    p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $95
    Qty:
    Pack:
    25mg
    Price:
    $382
    Qty:
  6. Description:

    Potent, selective PKA inhibitor

    Pack:
    500μg
    Price:
    $398
    Qty:
  7. Pack:
    1mg
    Price:
    $255
    Qty:
  8. Pack:
    1mg
    Price:
    $114
    Qty:
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