Product overview

Name Piceatannol
Purity >98%
Description Syk tyrosine kinase / JAK-1 inhibitor
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Biological Data

Biological description Syk tyrosine kinase inhibitor (IC50 = 1.53 µM). Also JAK-1 inhibitor. Analog of resveratrol. Shows many biological actions such as growth-inhibitory, anti-oxidant, anti-inflammatory, cardiovascular and pro-apoptotic effects.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (10mg/ml) or DMF
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 3,5,3',4'-Tetrahydroxystilbene
Molecular Weight 244.3
Chemical structure Piceatannol  [10083-24-6] Chemical Structure
Molecular Formula C14H12O4
CAS Number 10083-24-6
PubChem identifier 667639
SMILES C1=CC(=C(C=C1C=CC2=CC(=CC(=C2)O)O)O)O
InChiKey CDRPUGZCRXZLFL-OWOJBTEDSA-N

References for Piceatannol

References are publications that support the biological activity of the product
  • Biological activity of piceatannol: leaving the shadow of resveratrol.

    Piotrowska H et al (2012) Mutat Res 750(1) : 60-82.
  • Piceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.

    Chen WP et al (2009) Br J Pharmacol 157(3) : 381-91.
  • Piceatannol inhibits melanogenesis by its antioxidative actions.

    Yokozawa T et al (2007) Biol Pharm Bull 30(11) : 2007-11.

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