Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. 1  Review
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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  2. Description:

    Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  3. Description:

    Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  4. Description:

    Antibody to GAPDH - universal loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  5. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $316
    Qty:
  6. Description:

    Monoclonal antibody (IgM) to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  7. Description:

    Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Pack:
    25μg
    Price:
    $141
    Qty:
    Pack:
    100μg
    Price:
    $315
    Qty:
  8. 1  Review
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    Description:

    Antibody to HSP60 - loading control and mitochondrial marker for immunohistochemistry and immunocytochemistry. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Pack:
    25μg
    Price:
    $155
    Qty:
    Pack:
    100μg
    Price:
    $352
    Qty:
  9. Description:

    Antibody to Ki-67 - a widely used marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Human
    Pack:
    25μg
    Price:
    $139
    Qty:
    Pack:
    100μg
    Price:
    $310
    Qty:
  10. Description:

    Antibody to MAP2 - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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