Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 121-130 of 313

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  1. Pack:
    2mg
    Price:
    $143
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    Pack:
    5mg
    Price:
    $196
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    Pack:
    10mg
    Price:
    $341
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    50mg
    Price:
    $1,093
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  2. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
    Price:
    $201
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    Pack:
    1mg
    Price:
    $669
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  3. Pack:
    100μg
    Price:
    $243
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  4. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,242
    Qty:
  5. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
  6. Pack:
    1mg
    Price:
    $34
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    Pack:
    5mg
    Price:
    $117
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    Pack:
    10mg
    Price:
    $215
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    Pack:
    25mg
    Price:
    $452
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  7. Pack:
    10mg
    Price:
    $355
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    Pack:
    50mg
    Price:
    $1,410
    Qty:
  8. ICG 001 (HB0331)

    Description:

    Selective, competitive inhibitor of β-catenin/CBP interaction

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $234
    Qty:
  9. Pack:
    50mg
    Price:
    $108
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    Pack:
    100mg
    Price:
    $173
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    Pack:
    250mg
    Price:
    $350
    Qty:
    Pack:
    500mg
    Price:
    $647
    Qty:
  10. Description:

    Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $86
    Qty:
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