Target

Integrated stress response (ISR) inhibitor. Promotes pluripotent stem cell survival as part of the CEPT cocktail.

LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.

Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.

Non-ATP competitive Aurora A and B kinase inhibitor

Specific, non-ATP competitive Aurora A inhibitor

Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.

Potent 5-HT₃ receptor antagonist. Also α7 nAChR partial agonist. Activates α7Q79G-GlyR chimeric ion channels.

Novel, potent, subtype-selective TRPV3 inhibitor

Potent, selective, reversible T-type calcium channel blocker

Selective HDAC6 inhibitor