Proliferation, self-renewal, maintenance

Stem cells have the ability to replicate continually. Proliferation is when a cell multiplies but does not change its cell type. Self renewal is the process of a stem cell dividing to produce at least one copy of itself. Small molecules such as SB 203580 and PGE2 stimulate proliferation. Researchers can save up to 50% on small molecules which modulate stem cell proliferation, self-renewal and maintenance from Hello Bio - they are up to half the price of other suppliers. 

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  1. SB 216763 (HB1272)

    1  Review
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    Description:

    Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    50mg
    Price:
    $558
    Qty:
  2. SB 431542 (HB3555)

    4  Reviews
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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    5mg
    Price:
    $153
    Free trial
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    Pack:
    2x5mg
    Price:
    $240
    Qty:
    Pack:
    10mg
    Price:
    $233
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    Pack:
    25mg
    Price:
    $508
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    Pack:
    50mg
    Price:
    $959
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $154
    Qty:
  3. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty:
  4. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  5. Pack:
    250mg
    Price:
    $300
    Qty:
  6. Thiazovivin (HB3240)

    Description:

    Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $405
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    Pack:
    25mg
    Price:
    $645
    Qty:
  7. Troglitazone (HB2559)

    Description:

    Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.

    Purity:

    >97%

    Pack:
    25mg
    Price:
    $320
    Qty:
  8. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $164
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    Pack:
    25mg
    Price:
    $679
    Qty:
  9. 7  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $119
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    5x10mg
    Price:
    $754
    Qty:
    Pack:
    25mg
    Price:
    $325
    Qty:
    Pack:
    50mg
    Price:
    $564
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $408
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $680
    Qty:
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