Stem cells
Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These small molecules can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on high purity stem cell research tools such as ROCK inhibitor Y 27632, A83-01 and CHIR 99021 from Hello Bio - they are around half the price of other suppliers.
View products:  Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
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BrdU (5-Bromo-2′-deoxyuridine) (HB0979)
Description:Thymidine analog. Widely used to identify proliferating cells, enhances Yamanaka factor reprogramming
Purity:>98%
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CCG 1423 (HB3389)
Description:Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.
Purity:>99%
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CHIR 99021 (HB1261)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.
Purity:>98%
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CHIR 99021 trihydrochloride (HB1262)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.
Purity:>98%
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Compound E (HB3849)
Description:Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.
Purity:>98%
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Cyclopamine (HB2965)
Description:Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Purity:>98%
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DAPT (HB3345)
Description:γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.
Purity:>98%
