Stem cell signaling
Various signaling pathways are involved and can be modulated as part of stem cell processes such as differentiation, proliferation and reprogramming and small molecules such as Prostaglandin E2, XAV939 are used to modulate pathways. Researchers can save up to 50% on small molecules which modulate stem cell signaling pathways from Hello Bio - they are up to half the price of other suppliers.Â
17-AAG (HB3599)
Description:Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
Purity:>98%
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AMD 3100 octahydrochloride (HB2739)
Description:Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
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BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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Cyclopamine (HB2965)
Description:Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Purity:>98%
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Flurbiprofen (HB3049)
Description:Cyclooxygenase inhibitor. Regulates prostate stem cell antigen.
Purity:>99%
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Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
