PI3K/Akt/mTOR

STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.

Competitive, selective NOS inhibitor

Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

Potent, selective nNOS inhibitor

Competitive, selective PKC inhibitor

Potent, selective JAK2 inhibitor

Non-selective HDAC inhibitor

Selective STAT3 inhibitor

PI3K/AKT/mTOR signaling inhibitor. Antitumour activity.

Potent, non-competitive protein phosphatase inhibitor