PI3K/Akt/mTOR

Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

PKC inhibitor

Potent, selective GSK3 inhibitor

Potent MAP kinase kinase (MKK/MEK) inhibitor

Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.

Potent PKC inhibitor

Selective PKC inhibitor

Selective, non-competitive PKC / PKA inhibitor

Selective PKC / S6K inhibitor

Potent, selective PKC inhibitor